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Cenegenics alternatives are often in the form of a low-T center, A low-T center focuses on low testosterone but does not focus on the causation of low-T symptoms

Cenegenics Alternatives: More than a Low-T Center

Article at a Glance

  • A low-T center focuses on low testosterone and bringing it within normal range. Sufficient monitoring is necessary to minimize side effects and risk, which is often lacking in most low-t centers.
  • Cenegenics all-encompassing approach is superior to a low-T clinic. Age management physicians focus on treating the hormone imbalance and the symptoms, but also investigate the root cause of the imbalance.
  • Cenegenics focuses on boosting energy, losing weight, enhancing libido, improving mental acuity, and achieving better sleep.

A Google search for “Cenegenics alternatives” yields roughly 35,600 results, and it is no surprise why. The world of age management medicine has exploded since the inception of our physician-founded program in 1997. From Ehormones to HealthGAINS, Andrologix to Royal Medical Centers, many hormone therapy services have emerged in response to the growing number of adults seeking out solutions for low hormone levels. Yet, as more and more individuals continue to prioritize their health through their middle ages and beyond, many continue to ask: How do Cenegenics alternatives compare to the original age management program?

As with many trailblazers, Cenegenics is superior in a number of ways. We are considered the “Gold Standard” in the industry, and beyond offering the best services for hormone treatment , our program extends far beyond hormone replacement therapy (HRT) and age management alone. If you are exploring your options for achieving optimal health and are wondering whether you might be able to attain the same results from a Cenegenics alternative, take the time to read through the following guide. From our comprehensive age management solutions that address all facets of adult wellness to our team of industry-leading specialists, we have cultivated a program for which, simply put, there is no viable alternative.

Going Beyond the Scope of a Low-T Center: Cenegenics Age Management

While there are indeed plenty of low-testosterone clinics to choose from, none compares to the robust age management solutions available through Cenegenics. Yet, many patients considering an alternative to Cenegenics might wonder whether such a comprehensive health optimization Our team excels in enhancing health across these five pillars through evidence-based, physician-developed strategies. program is necessary. After all, if many of the issues associated with aging can be traced to hormonal changes, isn’t HRT enough? Not quite.

It is important to note that while hormone regulation is a critical element in a robust wellness program, for many adults, it is only one piece of the puzzle. Changing hormones can produce widespread effects, from impacting sleep duration and quality to posing ongoing weight challenges. Thus, while treating hormone imbalances themselves is a logical starting point for patients suffering from estrogen and testosterone deficiencies, a better approach is to treat not only the imbalance itself, but also the many frustrating symptoms it may produce, in concurrence.

physicians at a low-T center only focus on your testosterone levels, Cenegenics physicians focus on the root cause of your low testosterone, Cenegenics alternatives cannot compare to the all-encompassing Cenegenics Elite Health program

The Cenegenics difference lies in our commitment to helping you overcome all of the challenges associated with aging. We address health in the areas of sleep, cognition, weight management, libido, and energy levels, providing well-rounded yet individualized treatment to achieve real results. Our team excels in enhancing health across these five pillars through evidence-based, physician-developed strategies. Moreover, our approach is proactive: instead of waiting for the signs of serious age-related diseases to appear, we mitigate risk factors and facilitate optimal health. Our focus is not to simply bring patients within the “normal” ranges found in traditional medicine. In many cases, these readings are not actually healthy at all, and are based on the overall U.S. adult population which encompasses the 32% of people who are obese. We therefore target accurate representations of optimal health, going far beyond age management medicine.

For example, we adhere to the highest standards in heart disease prevention with the understanding that 1 in 4 fatalities are caused by heart events. [1] More alarmingly, 50% of people who experience a heart event were classified as “low risk” by the measures employed in traditional medicine. [2] We use carotid artery testing to detect risk of heart attack or stroke by measuring the thickness of artery walls. In addition to this and other forms of sophisticated heart health testing which are not used in traditional medicine, we perform an abundance of additional exhaustive testing and diagnostics, including 86 comprehensive labs. This allows our physicians to drill down and identify core conditions causing health issues such as low energy or inability to lose weight. Even expert physicians who are highly trained in optimal health cannot properly diagnose a patient without this extensive testing, which also includes neurocognitive testing, VO2 max, DEXA scans, and more to precisely measure all biologic and physiologic biomarkers, as well as physical performance and mental acuity.

Additionally, it must be noted that age-related factors such as hormonal decline are not the only issues responsible for causing sub-optimal health. Exercise and sleep, for example, are cornerstones for reducing the risk of age-related problems including:

  • Obesity
  • Frailty
  • Dementia
  • Heart disease
  • Cancer
  • Osteoporosis

With the addition of hormone regulation, the effectiveness of nutrition, exercise, and sleep prescriptions can produce tangible results for motivated patients. Cenegenics patients therefore experience the benefits of hormonal health along with many more. Burning fat and building muscle, optimizing cognitive function, achieving quality sleep, and improving both physical and sexual energy are just a few of the lasting advantages of program participation. Ultimately, patients who choose Cenegenics understand that hormone replacement is of little value without establishing good overall health.

Clinics that offer hormone replacement therapy alone give patients only a small glimpse into their overall health. Yet, Cenegenics clinicians understand how each hormone has a specific job, but overlaps the others to create a synergistic environment for improved wellness.

Our team also realizes that hormone imbalances can encroach on job performance– especially in a 21st century business landscape where poor lifestyle choices, diminished endocrine system, and ongoing career-related stress can collide. Because hormones perceptively alter sexual, physical, and cognitive functions, which often lead to psychological complications, our team takes a sophisticated approach to wellness optimization instead of narrowly addressing a single parameter of age management. In doing so, we guide our patients into an improved lifestyle, maximizing health potential to enjoy a more youthful way of life with the following benefits:

Improved Energy

Cenegenics addresses the addition of exercise to a person’s regimen as research suggests that obesity is strongly linked to low testosterone, Cenegenics alternatives do not address exercise as their main focus is low testosterone and not the root causes of the issue

By the age of 70, roughly 30% of muscle mass individuals had at the age of 20 is gone [4]. This often contributes to decreased strength, fatigue, and energy depletion. Our age management doctors specialize in determining whether lifestyle changes alone are enough to address declining energy levels associated with aging, or whether a more aggressive approach is needed to target an underlying cause of the symptom.

Better Sleep

A low-T center does not focus on sleep, Cenegenics focuses on patients getting better sleep as poor sleep quality can attribute to hormonal changes, Cenegenics alternatives may not address sleep issues such as sleep apnea or disordered breathing as a cause of low testosterone

Untreated sleep disorders increase the risk of death from any cause in older adults [5]. More than a third of Americans are poorly rested for more days out of the week than not, and nearly half the population (46%) is unable to achieve the recommended seven to eight hours of sleep every night [6].

While poor sleep is in certain cases attributed to hormonal changes, there are many other potential culprits. Specifically, there is a proven interplay between sleep and inflammation, especially in the cardiovascular system. Sleep-disordered breathing and obstructive sleep apnea, in particular, can be attributed to sleep issues for at least 24% of the population. By addressing sleep disorders, in addition to any contributing factors, Cenegenics physicians make the greatest possible improvement on both long- and short-term health in their patients.

Mental Acuity

It is in irrefutable fact that the mind changes with age. Yet, neural and cognitive functions are complex, and age-related changes to brain structure and function are not the same in all individuals. Moreover, age alone isn’t the only factor impacting focus, memory, and other cognitive functions. Lifestyle factors such as exercise, sleep, diet, alcohol consumption, and even caffeine intake can all influence brain health. Understanding the ways in which these factors affect the mind demands an extensive look into an individual’s current measures of health, medical history, and lifestyle. Through approaches such as nutraceuticals and prescriptive lifestyle adjustments, Cenegenics clinicians advise tailored preventive treatment programs to help patients minimize age-related cognitive decline.

Weight Loss

Cenegenics focuses on weight loss for obese patients as it can be a large contributor of low T, Cenegenics alternatives do not often focus on weight loss as part of their treatment plan of low T

Metabolic rate drops by 2% or more per decade after the age of 25 [7], making weight loss and weight regulation more challenging with age. However, it is important to understand that aging, and the fluctuations in hormone levels that go with it, cannot be solely blamed for the obesity epidemic. It is instead eating patterns that contribute to obesity, which is directly linked to morbidity from heart disease, cancer, diabetes, and high blood pressure [7]. Thus, any indication that a single hormone supplement will accomplish weight loss in itself is a falsehood, as there is no way to achieve sustainable weight loss without compliance to a healthy eating program.

Cenegenics physicians take into consideration the lifestyle factors, preferences, and nutritional needs of their patients to design a detailed dietary plan. In doing so, they help their patients make the transition towards mindful, healthy eating habits that will last, instead of dieting. The results are not only reductions in body fat, but also decreased risk of life-threatening conditions such as cardiovascular disease.

Increased Libido

A declining sex drive can take a toll on overall wellbeing, as well as the quality of a relationship. Low sexual interest can stem from a multitude of factors, including fatigue. Like weight management and sleep, addressing variances in libido necessitates a patient-centric approach. Our physicians therefore perform a comprehensive analysis into overall physical and mental health to determine the best course of action for each patient.

Cenegenics alternatives focus on increasing testosterone in order to increase libido, Cenegenics focuses on additional factors like weight management and sleep as low libido may stem from a multitude of factors

Overall, the comprehensive approach taken by Cenegenics is vastly different from those of most low-T clinics, many of which promise results with a few simple steps. True health optimization requires compliance with a demanding and comprehensive program. Low-testosterone clinics, conversely, advertise services such as medications shipped to you after a brief analysis. Unfortunately, these quick and easy approaches may overlook some significant indicators of health – which could have serious consequences.

How Cenegenics Differs from a Low-T Center: Unwavering Attention to Detail

Cenegenics clinical team take an all-encompassing approach compared to Cenegenics alternatives, The Cenegenics team ranges from phlebotomists to physicians in order to give the highest quality of patient care

Cenegenics’ comprehensive approach to health encompasses patient care from multiple sources, including wellness optimization physicians, exercise physiologists, phlebotomists, and nutrition & nutraceutical experts. They also look at the entire picture of patient health by taking into consideration key factors such as carbohydrate metabolism to observe the ways in which bioidentical hormones are impacting critical bodily functions.

Individualized Treatment

One important difference among Cenegenics and its competitors is our commitment to prioritizing the individual needs analysis. Our care providers treat each patient based on the specific nuances and combined circumstances impacting their health. While we understand that symptoms associated with low hormone levels may be one of the primary reasons why patients seek us out, our physicians also understand that a “one size fits all” modality is ineffective for treating these conditions. Instead, the complex interplay among nutrition, exercise, sleep, and genetic factors, among others, must all be considered and accounted for when developing a robust and effective health optimization plan.

To administer such a plan, Cenegenics collects in-depth, comprehensive lab values on patients at specific intervals. Contrast this with low-T centers, many of which boast a simple and easy three-step process. After the patient contacts the center, physicians from these low-cost options typically only perform a review of the patient’s sex hormone panel before prescribing medications. Yet, this significantly limits the physician’s understanding of how hormones are directly affecting carbohydrate and lipid metabolism, inflammatory markers, and kidney and liver function. More alarmingly, they may fail to address the treatment’s potential influence on prostate health. While low-T centers may perform lab work when subjective symptoms arise, Cenegenics is proactive in measuring the impact of bioidentical hormone use on prostate, kidney, and liver health, as well as other biomarkers.

By processing this information and regularly observing patients and patients’ biomarkers, our clinical team dynamically shifts and adjusts nutrition, exercise, and supplement goals and efforts, as needed, as patients respond and adapt over time. This allows us to make recommendations based on the individual’s needs analysis and prescribe only what will impact their biomarkers.

The Biomarkers of Aging

Only trained age management specialists can perform a comprehensive analysis of an individual’s biomarkers of age and provide individualized treatment based on these factors. Unlike our chronological age, the biomarkers of aging tell a different story. Made up of parameters such as muscle strength, cardiovascular performance, bone density, immunology, and mental acuity, they give age management specialists the most comprehensive overview of wellness when combined. Using this information, Cenegenics clinicians are able to develop customized exercise, nutrition, and supplementation programs – in addition to bioidentical hormone treatment fitting the precise needs of the individual.

Industry-Leading Specialists

age management medical practice, Cenegenics physicians differ from low-t center centers

Many low-cost clinics operate under one physician, while Cenegenics boasts 20 centers across the country supported by Cenegenics Partners, Center Physicians and Fellows trained in Age Management Medicine by the AMM Education Foundation. As our Partner and Director of Education for the Clinical Strategies for Healthy Aging course, Dr. Jeffrey Park Leake also co-wrote the Textbook of Age Management Medicine, available on Amazon. We pioneered the world’s largest age management practice, and with a focus on preventive care, have helped more than 35,000 patients worldwide dramatically improve their health and vitality. With optimal health as our primary focus, we bridge the gap between medicine and scientifically-based prevention, going far beyond addressing hormonal imbalances and achieving maintenance, not just repair.

We also hold our physicians against the highest set of standards to ensure the utmost quality of care for our patients. These specialists are highly trained in Cenegenics clinical tactics to aging, and only 1% of trainees meet the requirements needed to become a Cenegenics Physician Partner. Our physicians collaborate on complex patient health issues and are continually receiving clinical updates as proven, evidence-based science evolves to ensure each patient’s program remains cutting-edge and effective. Patients can therefore remain confident in the fact that health issues which arise can be detected early for preventive treatment, and that continuous monitoring will ensure their individualized Program is consistently updated to reflect emerging science and evolving goals.

The value of having a full team of health optimization specialists oversee your needs and progress through the program is beyond measure: it ensures every aspect of your health is being enriched to its fullest potential. Additionally, with a complete panel of specialists, we do not outsource:

  • lab services
  • diagnostic testing
  • clinical support
  • pharmacy items
  • nutraceuticals

This means all of the components of your wellness program will be overseen by Cenegenics and managed internally. Instead of waiting in a lab office, you will receive prompt and professional service through our phlebotomy network. Instead of going to multiple locations for testing, diagnostics are performed onsite for your convenience. We also have employed, onsite support staff, versus call center or remote health coaches. Finally, our patients receive custom pharmacy items, and efficaciously dosed, pharmaceutically tested, nutraceuticals with patented raw materials – instead of low-cost, generic retail supplements. In other words, Cenegenics believes that the quality of what goes into the body directly influences the quality of health outcomes.

A Better Patient Experience Over Cenegenics Alternatives

Cenegenics patients often have a better overall patient experience as compared to a low-T center, Cenegenics unwavering attention to detail helps patients combat low testosterone and its symptoms

While the attention to detail within Cenegenics program versus its alternatives is perhaps the most noteworthy difference, one final factor to bear in mind is the patient experience. While there is nothing wrong with seeking treatment elsewhere, lower-cost alternatives typically require more effort on the patient end. As a concierge, proactive medical service, the Cenegenics team takes significant measures to ensure compliance with a demanding, comprehensive program to potentiate real results and manage age-related disease risk. Through timely follow-ups, patient-focused care from day one, and an unwavering commitment to your precise wellness needs, our team ensures a positive experience in your journey towards optimal health.

Why a Low-T Center Is Not an Alternative to Cenegenics

A search for “Cenegenics alternatives” yields thousands of results, ranging from Ehormones to HealthGAINS, Andrologix to Royal Medical Centers, and it is no surprise why. The world of age management medicine has exploded since the inception of our physician-founded program in 1997. Many hormone therapy services have emerged in response to the growing number of adults seeking out solutions for low hormone levels, promising a low-cost few step solution. However none compare to the original Age Management Medical Practice, Cenegenics.

Cenegenics focuses on attention to detail, taking significant measures to ensure compliance with a demanding, comprehensive program to potentiate real results and manage age-related diseases. The accessibility to the Cenegenics clinical team – physician, nutrition expert, exercise physiologist and phlebotomist, allows timely follow-up in patient focused care to guarantee you are receiving an individualized plan designed specifically to accommodate your needs; Cenegenics is not a “one-size-fits-all” program.

Next Steps to Prioritizing Your Health with Cenegenics

Register for your complimentary phone consultation.

We hope the information above assisted you in your research process.

Key Resources

This guide was produced with contributions from the following key resources:

[1] Centers for Disease Control and Prevention. “Heart Disease Facts”. Retrieved from

[2] From Vulnerable Plaque to Vulnerable Patient—Part III: Executive Summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force Report. The American Journal of Cardiology. 2006.

[3] Boston, Gabriella. “Basal metabolic rate changes as you age.” Washington Post. 05 March 2013.

[4] Dennis, Helen. “Successful Aging: Causes of energy loss in older adults.” Los Angeles Daily News. 29 June 2015.

[5] Paudel et al. “Rest/Activity Rhythms and Mortality Rates in Older Men: MrOS Sleep Study.” Chronobiology International. 06 Apr. 2010.

[6] Sleep and tiredness survey. YouGov. 02 June 2015.

[7] Stanford Health Care. Retrieved from URL:

Additional Information For Cenegenics Age Management Program 

What is Cenegenics?

What is Age Management Medicine?

What Does Cenegenics Cost?

Cenegenics Elite Health Program: Why You Should Consider Age Management Your Next Investment

Anti-Aging vs. Age Management

Weight Loss on the Cenegenics Age Management Program

Defy Your Age™ with Cenegenics

What is Testosterone Replacement Therapy (TRT)?

Symptoms of stress can range from anxiety to inability to focus, Chronic stress puts individuals at higher risk for cardiac episodes including heart attack and stroke

Understanding Chronic Stress

Article at a Glance

Chronic stress can impact almost every facet of life and can manifest as:

  • Physical symptoms: increased blood pressure and heart rate, rapid breathing, chest or back pain, muscle cramps, upset stomach, low energy, increased sweating, and fainting.
  • Cognitive symptoms: increased anxiety and worry, racing thoughts, poor judgement, lack of focus, memory and concentration issues.
  • Behavioral symptoms: unhealthy responses to stress including decision to drink, use drugs or other harmful habits.
  • Emotional symptoms: anxiety, feeling overwhelmed, increased hostility, poor impulse control, tension, and unwillingness to cooperate.

Additional chronic stress can increase risk of serious disease such as diabetes, heart disease, heart attack and stroke.

Stress impacts nearly every single system in the body. It can weaken the immune system, impede functionality in the digestive and reproductive systems, increase risk of cardiovascular disease, and accelerate aging.[1] Optimal health is important to work performance, however – especially for professionals in high-power roles with many taxing responsibilities. When stress begins to affect cognitive function, including judgment, concentration, memory, as well as physical and emotional wellbeing, it becomes essential to address its impacts promptly. 

A healthy adaptational response to stress occurs over a short time frame. For minimal to no effects on long-term health, stress responses should be initiated quickly, maintained for a brief amount of time, and then turned off. On the other hand, problems arise when individuals experience an over-response to stress, or the stress response fails to shut off. A healthy response to stress is characterized by the following three steps:

  • The brain mediates the stressor, signaling the adrenal medulla to release adrenaline.
  • The hypothalamus, a region of the forebrain which coordinates the nervous system, works with the pituitary gland to trigger the slower maintenance response, signaling to the adrenal system to release hormones including cortisol.
  • Nerves react to the trigger, producing behavioral responses such as heightened awareness, focused attention, and reduced pain perception.

These actions controlled by the hypothalamic-pituitary-adrenal axis and sympathetic nervous system contribute to the body’s internal balance, or homeostasis, to optimize energy production and use. Because these systems influence other functions in the body; prolonged responses can have a damaging effect on health. [2]

Symptoms of stress can be both immediate and long-term. While there are many long-term consequences of chronic stress that should be considered to understand its full impact, for now, we will focus on short-term symptoms associated with the condition, categorized by type.

Physical Symptoms of Stress

The physical symptoms of stress can be experienced almost immediately upon exposure to stressors. Stress slows some bodily functions, such as the immune and digestive systems, while hastening others. For instance, blood pressure and pulse rate increase, and rapid breathing occurs. Other physical effects of stress can include sweating, back or chest pain, muscle cramps or spasms, headache, nervous twitches, and upset stomach. Low energy, dry mouth, difficulty swallowing, ringing in the ear, and cold or sweaty hands and feet are also physical symptoms of stress. In cases of extreme stress, fainting can also occur.[3]

Cognitive Symptoms of Stress

Acute stress can be advantageous and allow individuals to be hyper alter and make quick decisions, Chronic stress can lead to difficulty concentrating and memory problems

Acute stress can heighten awareness, allowing individuals to become hyperalert to their surroundings . This can be advantageous in certain professional circumstances – allowing for sharp and quick decision-making, for example. Yet, chronic stress actually has the opposite effect. With constant worrying, anxiety, and racing thoughts, individuals may experience poor judgment. Difficulty concentrating and memory problems are also common symptoms of chronic stress.[4] In professionals and executives, whose effectiveness in their role is largely determined by decision-making skills, the cognitive impacts of stress can take a devastating toll on one’s career.

Behavioral Symptoms of Stress

Behavioral symptoms of stress include negative habits such as nail biting and tobacco use to form, Chronic stress may lead individuals to turn to negative behaviors such as alcoholism and drug abuse

The negative impact of stress penetrates virtually every aspect of an individual’s life. In an attempt to escape stress factors, individuals often turn to unhealthy behaviors such as tobacco use, as well as drug or alcohol abuse. Over- or under-eating and decreasing frequency of exercise can also result from compounding stress. Individuals may adopt nervous habits like nail biting and pacing, and they may also become socially withdrawn. Procrastination and neglect of important responsibilities are additional characteristics of chronic stress; as some individuals use avoidance as an unhealthy coping mechanism.[5]

These negative behaviors can transcend into other areas of one’s life, too. With unhealthy behavioral responses to stress, decisions to drink, use drugs, or practice other harmful habits may also affect sleep quality, weight, libido, energy, and cognitive function. Optimizing these five areas of wellness is essential to job performance, because a well-rested individual who is also at their best both physically and mentally is better able to excel in their role. Therefore, the ability to deal with job-related stressors (or any other source of stress) in healthy, productive ways can support performance in the workplace, while also improving quality of life in one’s personal life, too.

Emotional Symptoms of Stress

Emotional symptoms of stress include increased agitation and may lead to social withdrawal, Chronic stress can progress into depression and other mental health conditions

The emotional symptoms of stress include anxiety and agitation, as well as feeling overwhelmed. Agitation can cause hostility, poor impulse control, tension, and uncooperativeness – qualities which sever ties among colleagues and other members of your professional network.[6] Because individuals with chronic stress tend to limit their social interaction, they may also begin to develop feelings of isolation and loneliness. The condition may also lead to feelings of insecurity and restlessness. Feeling generally unhappy is a common symptom of stress, and over the long term, this can progress into depression and other mental health conditions.[7]

While these symptoms are serious and need to be addressed, the effects of stress become even more critical if not treated. Over the long-term, the consequences of ongoing stress can have an extreme impact on a person’s mental, physical, emotional, and cognitive wellness. Impaired concentration and low energy levels are just two of the specific effects related to chronic stress that can directly diminish workplace performance. Cenegenics focuses on optimizing the five pillars of wellness – sleep, energy, libido, cognitive function, and weight management – with proven age management medicine to help professionals feel and perform their best professionally.

Long-Term Effects of Stress

Chronic stress has dangerous, multifarious implications: not only can stress create new problems, it may also exacerbate existing ones. For executives and professionals whose busy day-to-day routines are already impacted by the demands of juggling a multitude of responsibilities, the effects of chronic stress can be more pronounced than in the average individual. The physical and mental toll the condition takes on people can ultimately transcend to the workplace, leading to conditions like lack of sleep, focus, and energy which can impede long-term goal achievement and overall career success. Here are just a few of the specific ways stress can have a lasting impact on health.

Physical Consequences of Long-Term Stress

The long-term physical effects of chronic stress are nearly too vast to measure. When stress is constant, the same life-saving response your body produces in acute stress can suppress your immune system, making you more vulnerable to disease and illness. Individuals with chronic stress are more prone to developing colds and other sicknesses, and there is even an established link between stress-related disorders and autoimmune diseases such as Crohn’s disease, rheumatoid arthritis, and psoriasis [8]. These conditions can lead to absenteeism and energy depletion, which could have a compounding, negative effect on work performance. Researchers believe that when stress is severe, the body may lose control of cortisol over the immune system, contributing to increased inflammation. This can also lead to a range of serious health conditions, including heart disease, high blood pressure, and diabetes. Left untreated, these factors can contribute to potentially fatal conditions including heart attack and stroke [9].

Chronic stress can lead to increased risk of serious health conditions including heart disease and high blood pressure, Physical symptoms of stress can vary but may progress into potentially fatal conditions including heart attack and stroke

Stress can also impact physical appearance, leading to skin and hair issues including psoriasis, eczema, hair loss, and acne. When it affects diet and exercise, it may also lead to obesity or other eating disorders. Being overweight increases the risk of fatigue, as decreased sleep duration and quality are directly associated with increased body weight [10]. Thus, the effects of stress tend to snowball: fatigue also impairs brain activity, which makes it impossible to contribute to your fullest potential at work [11]. The inflammatory response can also irritate the colon, causing conditions such as gastritis and ulcerative colitis over time.

The impact of stress is so pronounced that it can even cause issues in the reproductive system. In women, it can cause menstrual problems, while it may cause sexual dysfunction such as premature ejaculation and impotence in men. Loss of sexual desire is also potential side effect of stress experienced in both men and women [12].

Additionally, while stress can contribute to obesity which can in turn cause fatigue, stress itself also often has a major impact on sleep. Unfortunately, the stress/sleep relationship often forms a dangerous cycle, in which the heightened state of alertness produced by chronic stress prevents sleep, but lack of sleep continues to cause added stress. In fact, adults who sleep fewer than the recommended eight hours per night report a higher stress level than those who sleep at least eight hours each night. Stress often causes individuals to lie awake at night with anxiety, and this lack of sleep can compound the physical damage caused by stress. Even minimal sleep deprivation or poor sleep quality can contribute to serious health issues like obesity and high blood pressure, as well as impaired memory and judgment [13]. While alertness is essential to navigating daily challenges in most executive, managerial, and other professional roles, it is also necessary for a host of other day-to-day activities, including driving and maintaining awareness of your general surroundings.

Additional Consequences of Chronic Stress

Additional symptoms of stress include depression and chronic anxiety

Chronic stress can contribute to clinical depression, chronic anxiety states, and addictive disorders. One of the main reasons the condition is so dangerous is because of its notorious snowball effect: it may only impact a few isolated areas of a person’s life at first, but these consequences tend to ripple outwards. The example of stress’s effect on sleep above showcases this relationship: while chronic stress itself can cause impaired judgment, it can also cause lack of sleep, which has an additional impact on decision making abilities. Thus, the lasting consequences of stress are often too significant to measure, and instead of affecting an individual in a linear fashion, it often produces a far-reaching web of consequences. Oftentimes, it penetrates the most critical realms of wellness in profound ways, including sleep, energy, weight, libido, and cognitive function.

These very pillars are the foundation on which the Cenegenics program was built. By finding solutions to improve in these five realms, effective stress management becomes a natural byproduct. For example, Cenegenics tailored programs provide solutions catered to each individual’s needs for optimizing nutrition, achieving better sleep, and driving energy levels, which can be effective tools for managing stress.

Understanding Chronic Stress vs Acute Stress – In Conclusion

Stress can impact nearly every single system in the body, and professionals in high-power roles with many taxing responsibilities are at in increased risk. Physical symptoms of stress can be experienced almost immediately upon exposure to stressors. Cognitive symptoms of stress such as constant worrying, anxiety, and racing thoughts can lead to poor judgment.

In an attempt to escape stress factors, individuals often turn to unhealthy behaviors such as tobacco use, as well as drug or alcohol abuse. These behaviors can lead to emotional symptoms and even progress into depression and other mental health conditions.

Over the long-term, the consequences of ongoing stress can have an extreme impact on a person’s mental, physical, emotional, and cognitive wellness. Cenegenics helps individuals with effectively managing stress by optimizing the five pillars of wellness – sleep, energy, libido, cognitive function, and weight management – with proven age management medicine to help professionals feel and perform their best professionally.

Contact Cenegenics to find out how our personalized, physician-developed age management solutions can help you treat your stress before you suffer long-term effects.

Next Steps: Managing Stress with Cenegenics

Register for your complimentary phone consultation.

We hope the information above assisted you in your research process.

Key Resources in Understanding Chronic Stress

This guide was produced with contributions from the following key resources:

The Cenegenics Education and Research Foundation

The Textbook of Age Management Medicine Volume 1: Mastering Healthy Aging Nutrition, Exercise and Hormone Replacement Therapy

Available for purchase here

The Textbook of Age Management Medicine Volume 2: Mastering Healthy Aging Nutrition, Exercise and Hormone Replacement Therapy

Available for purchase here

Textbook Authors:

Jeffrey Park Leake, M.D., CPT

Dr. Jeffery Park Leake is the Partner and Director for Physician Training and Certification for Cenegenics Las Vegas. He specializes in age management and wellness and has trained over 600 physicians worldwide.

Todd David Greenberg, M.D., CSCS

Dr. Todd Greenberg is a practicing physician with a broad range of expertise, including wellness, exercise, sports injuries, and MRI of sports injuries. He is a Radiology Clinical Associate Professor at the University of Washington.

Additional Information on Effectively Managing Stress

How Cenegenics Can Help Relieve Stress in Executives & Professionals

Types of Stress: Understanding Stressors

Why Can’t I Sleep? – Clinical Explanations

Healthy Heart: What is Heart Disease? Preventative Steps and Recognizing Symptoms

Building a Nutritional Plan: Food for Weight Loss

Weight Loss: Role of Exercise

What is Age Management Medicine?

What is Cenegenics?

Defy Your Age™ with Cenegenics

Sources on Managing Stress

[1] Segal et al. “Stress Symptoms, Signs, and Causes.” HELPGUIDEORG INTERNATIONAL. July 2018. Retrieved from URL:

[2] Stöppler, Melissa Conrad, MD. “Stress.” Retrieved from URL:

[3] Nordqvist, Christian. “Why stress happens and how to manage it.” Medical News Today. 28 Nov. 2017. Retrieved from URL:

[4] Segal et al, see above.

[5] “Stress symptoms: Effects on your body and behavior.” Mayo Clinic. 28 April 2016. Retrieved from URL:

[6] “Understanding Agitation.” Depression and Bipolar Support Alliance. Retrieved from URL:

[7] Segal et al, see above.

[8] Song et al. “Association of Stress-Related Disorders With Subsequent Autoimmune Disease.” Journal of the American Medical Association. 19 June 2018. Retrieved from URL:

[9] “The Link Between Autoimmune Diseases and PTSD.” Retrieved from URL:

[10] Hargens, et al. “Association between sleep disorders, obesity, and exercise: a review.” Nature and Science of Sleep. 1 Mar. 2013. Retrieved from URL:

 [11] Tanaka, et al. “Effects of Mental Fatigue on Brain Activity and Cognitive Performance: A Magnetoencephalography Study.” Department of Physiology, Osaka City University Graduate School of Medicine. 01 Jul. 2015. px

[12] Karriem-Norwood, Varnada, MD. “Stress: Symptoms.” WebMD. 11 July 2017. Retrieved from URL:

[13] “Stress and Sleep.” American Psychology Association. Retrieved from URL:

[14] Song et al. “Association of Stress-Related Disorders With Subsequent Autoimmune Disease.” Journal of the American Medical Association. 19 June 2018. Retrieved from URL:

Understanding how to deal with stressors can help decrease your risk of health problems and tarnishing long-term wellness, Business professionals often experience different types of stress including acute stress that can progress to chronic stress when not managed properly

Understanding How to Deal with Stressors

Article at a Glance

  • Stress is the body’s natural response to threats, and it is important to be able to distinguish the way the body experiences the three main types of stress: acute, episodic acute and chronic stress.
  • Internal stress factors come from within and can be caused by unrealistic expectation, pessimism, uncertainty, and negative self-talk.
  • External stress factors can include being too busy, feeling unable to complete everything on time.
  • Chronic stress can result in impaired cognitive function, weight gain, and a number of unfavorable symptoms.

Stress is the body’s normal response to threats. Yet, while it affects everyone in at least one way, not all forms of stress are the same – or even healthy. For professionals in positions associated with high levels of stress, it’s especially important to recognize the differences among the ways in which the body experiences stress.

Different Types of Stress

There are three main types of stress, each of which elicits a unique response in the body:

  • Acute stress
  • Episodic acute stress
  • Chronic Stress

Acute Stress

The demands of the near future and recent past cause acute stress, the most common form of stress. Work deadlines, exhilarating experiences, and short-term dilemmas can all cause acute stress. This form of stress is fleeting and does not have the potential to do long-term physical damage. In fact, acute stress can actually be considered “good” stress, because it helps executives and professionals perform better in challenging scenarios. Whether it is preparing for an important meeting or thinking quickly to rectify an unexpected issue, the body responds to perceived threats with quicker breathing and pulse, allowing you to use more oxygen and increase activity to perform better.[1] The danger to your health and work performance does not occur until acute stress becomes chronic stress, which is discussed below.

Episodic Acute Stress 

Individuals who always seem to be “on the edge of their seats,” often labeled as “Type A” personalities, are most likely to have episodic acute stress. While these individuals often embody characteristics that help them excel in the workplace, including the ability to multitask well and a sense of competitiveness that can lead to goal completion, they also face a tremendous amount of stress because they juggle many responsibilities and are pressured by time constraints.[2]  Cardiologists have concluded that these individuals are much more likely to have heart disease and high blood pressure than others, and face difficulties in organizing self-inflicted demands and pressures. Because these barriers to health can negatively impact work performance, individuals facing episodic acute stress must find ways to manage their stressors in a healthy way to ensure long-term wellness.[3]

Chronic Stress

By nature, stress is supposed to be temporary. Once the body recovers from fight or flight mode, you should be able to recover physically: your heart rate should return to normal and muscles should relax. Yet, chronic stress occurs even when real, physical danger is not present. It happens when a person is never able to escape their causes of stress but stops seeking solutions. Sometimes, it may be caused by a traumatic experience. While people can become used to and even comfortable with chronic stress, its effects are long-lasting and detrimental to health. Chronic stress is the most harmful type of stress and can have a number of effects on your body, mood, and behavior. If action is not taken, this form of stress can create or worsen health problems, including limited concentration, inhibited sleep, and problems with personal relationships – all of which can eventually lead to energy depletion and poor performance in the workplace.[4]

Understanding How to Deal with Stressors: Identifying Stress Factors

Our fight or flight response is influenced by both external and internal factors. While both types can produce similar effects, they can also both be addressed and managed effectively. Understanding the differences between these two sources can help pinpoint your greatest sources of stress.

Internal Stress Factors

As their name suggests, internal stressors come from within. These stressors stem from an individual’s perception of themselves compared to where they think they should be in life. Internal stressors play a role in one’s ability to handle external sources of stress, which is why it becomes critically important to address any internal stressors, if present, first. Common internal stress factors include:

  • The inability to accept uncertainty
  • Rigid thinking
  • Inflexibility
  • Pessimism
  • Unrealistic expectations of perfectionism
  • Negative self-talk

External Stress Factors

Common external stress factors include:

  • Job-related stress
  • Major life changes
    • Death of a family member
    • Divorce
    • Retirement
  • Family problems and relationship difficulties
  • Being too busy
  • The feeling of being unable to get everything done

Unfortunately, this tends to be a common feeling among individuals holding demanding jobs or maintaining positions of power in the workplace. Because the stress associated with high-power positions is unavoidable for most career-oriented professionals, the solution for managing chronic stress lies in first addressing its effects. By overcoming fatigue, for instance, professionals can become sharper and more alert, and ultimately, more engaged and focused at work. Likewise, tackling many of the additional challenges that tend to accompany aging, such as cognitive impairment and weight gain, can also create a healthier individual who is better able to manage the stress of their career.

Ultimately, stress is different for each individual, and the factors which may elicit a response in one person may not affect another. Regardless of the stressor, however, chronic stress can produce a number of unfavorable symptoms in those who suffer from it. Thus, addressing its effects proactively – before they escalate and cause irreversible career or relationship damage – is critical for people who face chronic stress.

Impact of Acute & Chronic Stress: In Conclusion

Stress can affect people in various ways, but for professionals dealing with high levels of stress, it is especially important to recognize the type of stress you are undergoing and the effect it can have on your body. All types of stress, if not managed, are all capable of increasing your risk for health problems and tarnishing long-term wellness.

Our fight or flight response is influenced by both external stressors and internal stressors. Internal stressors stem from an individual’s perception of themselves, and it is important to address them first to be able to handle any external stress factors. External stressors include job-related stress, family problems, relationship issues, etc. If such effects are left unmanaged, there is potential for unfavorable symptoms and health-related consequences of chronic stress.

Cenegenics’ expert clinicians help you overcome high levels of stress by catering to the rigorous demands that life presents.  Each program is individually tailored to your specific needs and is designed to help mitigate stress, both immediately and over a long-term basis.

Next Steps: Get a Handle Your Stressors 

Register for your complimentary phone consultation.

We hope the information above assisted you in your research process.

Key Resources on Stress Management

This guide was produced with contributions from the following key resources:

[1] “5 Things You Should Know About Stress.” National Institute of Mental Health. Retrieved from URL:

[2] Tirado, Bernando, PMP. “Working With a Type A Personality.” Psychology Today. 30 Jan. 2012. Retrieved from URL:

[3] “Stress: The different kinds of stress.” American Psychological Association. Retrieved from URL:

[4] Nordqvist, Christian. “Why stress happens and how to manage it.” Medical News Today. 28 Nov. 2017. Retrieved from URL:

Additional Information on Stress Reduction

How Cenegenics Can Help Relieve Stress in Executives & Professionals

Symptoms and Long-Term Consequences of Stress

What is Age Management Medicine?

What is Cenegenics?

Defy Your Age™ With Cenegenics

Clinical explanations for understanding “why can’t I sleep” may include physical barriers such as weight and sleep apnea, consequences of sleep deprivation can range from impaired intention to increased risk of morbidity and mortality

Why Can’t I Sleep? – Clinical Explanations & Tips on How to Fall Asleep

Article at a Glance

  • Short-term consequences of sleep deprivation include deceased attention and memory retention, sleepiness, increased risk of accidents, increased hunger and decreased mood.
  • Long-term consequences of sleep deprivation includes increased risk of disease and death, increased obesity, and increased risk of chronic diseases such as type 2 diabetes, heart disease, and depression.
  • Weight, sleep apnea, and hypogonadism can be physical barriers to healthy sleep.
  • Tips on how to fall asleep include decreasing light exposure, lowering temperature of the room, exercise earlier in the day, and avoid caffeine and exercise closer to bed time.

Sleep has been hailed as a critical factor contributing to our overall wellness for many decades, but diet and exercise are often perceived as the ultimate priorities for effective health management. Yet, nutrition and fitness cannot compensate for the effects of poor sleep quality. In fact, both the length of time we spend sleeping each night as well as the quality of the sleep we achieve play a major role in our vitality, largely dictating our risk of developing serious diseases such as type 2 diabetes and cardiovascular disease.

It can be safely assumed that everyone has experienced a poor night of sleep at least once in their lifetime, and although sleep deprivation is rampant across the country, it is impossible to gauge just how many individuals are affected by lost sleep. What we do know is that roughly 50-70 million U.S. adults have a sleep disorder.[1] With that said, even undiagnosed sleep issues raise serious concerns: both repeated instances of severe sleep deprivation as well as chronic sleep deprivation can have negative impacts on key health outcomes.

Within this guide, we will take a closer look at the complex ways in which sleep affects our health. We will also explore the most common causes of disordered sleep and present tactics for overcoming these and other impediments to achieving ample, quality sleep.

Short and Long-Term Consequences of Sleep Deprivation

Consequences of sleep deprivation can have short term and long term effects, short term consequences of sleep deprivation may include problems with memory to increased moodiness and hunger, long term consequences of sleep deprivation include increased risk of developing chronic diseases such as cardiovascular disease and type 2 diabetes

The Textbook of Age
Management Medicine: Volume 1
highlights both short- and long-term
consequences of sleep deprivation. On a short-term basis, individuals who have
recently experienced lack of sleep may experience:

On a long-term
basis, consequences of sleep deprivation include:

Yet, the question remains: Why does lack of sleep increase our risk of these serious health issues? While there is still much to be learned about the impact of sleep on the body, we do know inflammation certainly plays a role in the relationship.

Sleep and Inflammation

Inflammation is one of the long term consequences of sleep deprivation, inflammation due to sleep deprivation is a large contributor in the development of cardiovascular disease

Inflammation is a well-established agent in the development of cardiovascular disease. A sustained increase in low-density lipoprotein (LPL, also known as the “bad” cholesterol), results in an accumulation of LDL in previously damaged arterial walls. This results in an inflammatory response that propagates plaque formation, thereby contributing to cardiovascular disease.

In the Textbook of Age Management Medicine: Volume 1, the relationship between sleep and inflammation is explored in great detail. In summation, sleep deprivation is inversely associated with plaque formation and coronary artery calcification in middle-aged adults. Sleep deprivation is also inversely associated with the thickness of the carotid intima media, or the innermost layer of artery walls. Several pro-inflammatory markers are inversely associated with sleep duration. In other words, the fewer hours a person sleeps, the more likely they are to experience elevated levels of inflammatory markers. In fact, these markers can be elevated in as little as one night of complete missed sleep. Because pro-inflammatory reactions are linked to a host of serious health conditions, such as stroke, cardiovascular disease, and type 2 diabetes, achieving the recommended number of hours of sleep each night is essential to long-term wellness.

Yet, while it is abundantly clear that sleep quality and duration are critical to health, many individuals still struggle to achieve a restful night of sleep. What are the most predominant barriers preventing us from achieving quality sleep?

Why Can’t I Sleep – Physical Barriers

There are many physical barriers that may explain “why can’t I sleep”, sleep apnea and weight regulation are large contributors as barriers to healthy sleep

There are many possible causes behind sleep deprivation, which is why the issue cannot be met with a “one-size-fits-all” approach to treatment. The inability to get to sleep – and remain sleeping for a full seven to nine hours – can be a result of either physical or psychological difficulties. For individuals struggling with psychological barriers, behavioral and cognitive treatments can be explored to enhance sleep without medical intervention.

With that said, many sleep issues are related to physical issues. Below, we’ll explore some of the most prevalent physical barriers to sleep.

Sleep Apnea

Obstructive sleep apnea (OSA) occurs when the airflow is insufficient for metabolic demands. The collapse of the pharynx results in this obstruction: when muscle dilator activity becomes insufficient to maintain the pharynx, obstruction occurs.

Weight Regulation

Weight regulation is a key player in the prevention and treatment of OSA. Results of a randomized control study of patients with type 2 diabetes and an average BMI of 36 and an average AHI of 23.2 show individuals who lost 22 pounds or more in a one-year period witnessed an improvement of 9.7 in their AHI scores. They were also three times as likely to have a complete remission of OSA. The reduction of AHI scores was directly related to the degree of reduction in weight. It can therefore be concluded that OSA could simply be considered a complication of obesity in many cases.[3]

Weight loss, like sleep complications, cannot be approached the same way for every patient. A combination of reduction in calories, adherence to a healthy eating plan with restricted or no intake of processed foods, and a tailored exercise program can be personalized to meet the weight loss needs and goals, as well as the personal preferences and lifestyle considerations, of each patient. Compliance is the most critical factor of all weight loss endeavors, which is why starting with a patient-oriented approach is essential.

Hypogonadism and Sleep

There is a suspected relationship between sleep disorders and hormones. Specifically, testosterone impacts the organization of circadian rhythms and timing of sleep. This relationship takes on a cyclical pattern: total sleep deprivation can also lower testosterone.

Additionally, the Textbook of Age Management Medicine: Volume 1 indicates there is a relationship among hypogonadism, or the failure of the reproductive organs to produce appropriate hormone levels, and OSA. The text examines study findings which point to a significant negative correlation of testosterone levels with AHI, indicating that low testosterone is associated with higher OSA symptoms.

Testosterone has been observed to have a destabilizing effect on ventilation. Leuprolide used to treat androgen deprivation has been shown to increase apneic episodes, but it should be noted that these findings were discovered in studies performed on obese men. With that said, similar findings have been observed in hypogonadal men treated with testosterone replacement.

Hypogonadism in males can either be primary, meaning it originates from a problem in the testicles, or secondary. In the latter case, low hormone levels could result from an issue in the pituitary gland, or the part of the brain signaling the production of testosterone. This can be either an inherited trait or acquired as a result of injury, infection, normal aging, or obesity.[4]

The most effective treatment of hypogonadism is therefore dependent on its underlying cause. In obese patients, for example, dietary and lifestyle changes can be prescribed to manage hypogonadism. Testosterone replacement therapy is also a viable form of treatment for many men and can result in increased energy, libido, erectile function, and an overall improved sense of wellbeing, in addition to improved sleep cycles. If the condition is a result of a pituitary issue, pituitary hormones may be administered to restore fertility and stimulate the production of sperm.

Other Sleep Impediments

Blue light from devices such as computers and smart phones can answer the question “why can’t I sleep” for many patients, exposure to certain types of light can be a barrier to healthy sleep, tips on how to fall asleep include turning off devices to create a dark room and lowering the temperature to create a better sleeping environment

In addition to the factors described above, there are a number of other lifestyle considerations that could inhibit proper sleep. Sleep hygiene, a term that was coined in the late 1970s, aims to control environmental and behavioral factors that can promote better quality sleep through certain habits and practices. Worry and stress, the intake of stimulants such as alcohol, caffeine, and nicotine, failure to establish a regular sleep schedule, and exposure to light (including blue light from devices such as smart phones and tablets) can all impair sleep hygiene.[5]

Tips on How to Fall Asleep

Beyond treating known issues contributing to sleep problems such as obesity, OSA, and hormone imbalances, quality sleep may be achieved by making some simple adjustments to your daily routine. Here are some tips worth considering, which D’Alessandro recommends both for his clients and anyone seeking improved sleep behaviors:

  1. Spend at least 20 minutes in a dark, cool room prior to going to sleep. This includes staying away from both handheld devices such as tablets and smart phones as well as larger technology, including televisions. The light from these devices can alter the body’s natural rhythm, making it more difficult to ease into deep sleep.
  2. Lower the temperature. A decrease in core temperature is necessary for entering REM sleep. Elevated temperatures, on the other hand, can cause restlessness and poor sleep.
  3. Avoid caffeine and exercise sessions too close to bed time. These factors can lead to increases in heart rate and blood pressure. Exercising and taking in caffeine too close to your normal bedtime may therefore make it difficult to bring your vitals down to baseline measures when it is time to sleep.
  4. Consider taking naps. When taken early in the afternoon or earlier in the day, naps of no more than 30 minutes have shown to improve cognition and focus. The catch is that limiting naps to 30 minutes or less is the required “sweet spot” needed to reap the benefits: any longer and you may experience an adverse effect, feeling groggy upon waking up. Additionally, naps should also be taken in a cool, dark place.[6]
  5. Exercise and weight train early, if possible. The increased muscle protein and fuel breakdown resulting from exercise requires our body to crave more recovery. Therefore, your body will make a more concerted effort to enter deep sleep if you work out regularly. You may also be more likely to stay asleep. Again, however, be mindful of avoiding exercise in the hours leading up to your normal bedtime.

The Solution for Sleep in Middle Age & Beyond

Cenegenics physicians provide more than quick fixes on how to fall asleep, Cenegenics physicians examine the reasons why you can’t sleep and attempt to alleviate the consequences of sleep deprivation through expert treatment that will better your sleep quality

Sleep is critical to mental and physical functionality at every stage of life, but it may have the greatest potential to be impacted as we age. When individuals experience natural age-related changes such as a decline in metabolism and hormonal variations, they may become more susceptible to conditions such as OSA, obesity, and other factors that influence sleep duration and quality. Thus, treating the underlying conditions contributing to sleep deprivation – rather than providing “quick fixes” for sleep issues – is essential to achieving lasting results.

Clinicians specializing in age management are therefore best equipped for helping middle-aged and older populations achieve better sleep. These experts take an all-encompassing approach to treatment, factoring in all of the different biomarkers which could impact sleep quality and duration. Through exercise, nutrition, and other lifestyle recommendations along with medical treatment if needed, they can help patients achieve better sleep patterns to make lasting improvements in sleep quality and duration, as well as overall wellness.

Key Resources on How to Fall Asleep

This guide was produced with contributions from the following key resources:

Joshua D’Alessandro

Nutrition and Exercise Counselor | Cenegenics New York City

The Cenegenics Education and Research Foundation

The Textbook of Age
Management Medicine Volume 1: Mastering Healthy Aging Nutrition, Exercise and
Hormone Replacement Therapy

Available on Amazon

Textbook Authors:

Jeffrey Park Leake, M.D., CPT

Dr. Jeffrey Park Leake is a Partner and Director of Education at Cenegenics Elite Health specializing in age management and wellness. Having trained hundreds of physicians worldwide, Dr. Leake is also the Director of Education for the Clinical Strategies for Healthy Aging course at AMM Education Foundation.

Todd David Greenberg, M.D., CSCS

Dr. Todd Greenberg is a practicing physician with a broad range of expertise, including wellness, exercise, sports injuries, and MRI of sports injuries. He is a Radiology Clinical Associate Professor at the University of Washington.

Next Steps to Combating the Consequences of Sleep Deprivation

Register for your complimentary phone consultation.

We hope the information above assisted you in your research process.

Additional Information on Why I Can’t Sleep

Sleep Apnea – What is it?

Sleep Stages

What is Age Management Medicine?

Defy Your Age

Watch Now: 3 Tips for Better Sleep

Sources on Sleep Disorders

[1] “Sleep and Sleep Disorder Statistics.” American Sleep Association. Retrieved from URL:

[2] “Sleep Deprivation: Symptoms, Causes, Treatments.” American Sleep Association. Retrieved from URL:

[3] Foster et al. “A Randomized study on the effect of weight loss on obstructive sleep apnea among obese patients with type 2 diabetes: the Sleep AHEAD study.” Archives of Internal Medicine. 28 Sept. 2009. Retrieved from URL:

[4] “Male hypogonadism: Symptoms and treatment.” Journal of Advanced Pharmaceutical Technology & Research. Jul-Sept 2010. Retrieved from URL:

[5] “Sleep Hygiene.” American Sleep Association. Retrieved from URL:

[6] Kutscher, S.J. “Sleep and Athletic Performance.” Principles and Practices of Sleep Medicine. 646-652. 10.1016/B978-0-323-24288-2.00064-7.

Obstructive sleep apnea occurs when airflow repeatedly stops and starts during sleep, obstructive sleep apnea symptoms can range from loud snoring to decreased libido, you may want to speak to a Cenegenics physician to understand how to diagnose sleep apnea and how sleep apnea is treated

Obstructive Sleep Apnea: What is it?

Article at a Glance

  • Obstructive sleep apnea (OSA) is a common sleep disorder in which your breaths become shallow or you stop breathing multiple times throughout the night.
  • OSA can be characterized by loud snoring, daytime sleepiness, and abrupt awakenings accompanied by gasps or choking sounds.
  • Obstructive sleep apnea is diagnosed via a full-night polysomnography and can be treated with PAP therapy, surgery, retainer devices or pharmaceuticals.
  • Weight can be one of the causes for OSA, so weight management may be a consideration when formulating a treatment plan.

Obstructive sleep apnea (OSA) occurs when the airflow is insufficient for metabolic demands. The collapse of the pharynx results in this obstruction: when muscle dilator activity becomes insufficient to maintain the pharynx, obstruction occurs.

OSA is an epidemic largely affecting obese individuals. While prevalence in the U.S. is estimated at 2% to 24% of the population, it is likely closer to the upper margin of this range because many patients are undiagnosed. In specific, OSA is moderately associated with a body mass index (BMI) of greater than 35, as well as hypertension and an increase in age up to 65 years. It also occurs more often in men than women, at a ratio of 2-3:1.[1]

Obstructive Sleep Apnea Symptoms

Obstructive sleep apnea symptoms can include:

  • loud snoring
  • excessive daytime sleepiness
  • episodes of breathing cessation during sleep
  • abrupt awakenings accompanied by gasps or sounds of choking
  • Morning headaches
  • decreased libido
  • difficulty concentrating
  • mood changes

While not everyone who snores has OSA, it is still recommended for snorers and individuals experiencing other symptoms to seek professional input from a physician.

How to Diagnose Sleep Apnea

To form a diagnosis, physicians will recommend patients to undergo full-night polysomnography, either in-lab or at home with a portable monitor. The test will measure critical parameters such as heart rate, leg movements, breathing patterns, and oxygen saturation. The number of respiratory events, including apnea (the repeated stopping and starting of breath), will be recorded to form the patient’s Apnea/Hypoapnea Index (AHI) score. Diagnoses are made at the following rates of interrupted breathing:

  • Mild: More than five times per hour, but fewer than 15
  • Moderate: More than 15 times per hour, but fewer than 30
  • Severe: 30 or more times per hour

Treatment of OSA

Depending on the findings, the physician may recommend treatments such as changing the sleeping position or the implementation of oral appliances. These appliances include mandibular reposition appliances which hold the jaw in place, as well as tongue retaining devices, which hold the tongue in a forward position to optimize airflow. In certain individuals, surgery may also be recommended to resolve sleep apnea. Removal of the tonsils and/or adenoids, for instance, may facilitate an improved airflow. While pharmacology is not typically a primary treatment option, limited corticosteroid use may improve airflow in patients with concurrent rhinitis.

One viable treatment option for all levels of OSA is positive airway pressure (PAP) therapy. Machines consisting of a mask to cover the nose and mouth, as well as a tube connecting to a motor which blows air into the tube, can help to ensure ample levels of air are reaching individuals while they sleep. Yet, compliance with PAP is poor, with 46% to 83% of patients being noncompliant.[2] Thus, where applicable, alternate therapies should be considered. In individuals with a BMI greater than 25, weight loss is one behavioral therapy that should be explored.

Next Steps on How to Diagnose Sleep Apnea

Register for your complimentary phone consultation.

We hope the information above assisted you in your research process

Key Resources on OSA

This guide was produced with contributions from the following key resources:

Joshua D’Alessandro

Nutrition and Exercise Counselor | Cenegenics New York City

The Cenegenics Education and Research Foundation

The Textbook of Age Management Medicine Volume 1: Mastering Healthy Aging Nutrition, Exercise and Hormone Replacement Therapy

Available on Amazon

Textbook Authors:

Jeffrey Park Leake, M.D., CPT

Dr. Jeffrey Park Leake is a Partner and Director of Education at Cenegenics Elite Health specializing in age management and wellness. Having trained hundreds of physicians worldwide, Dr. Leake is also the Director of Education for the Clinical Strategies for Healthy Aging course at AMM Education Foundation.

Todd David Greenberg, M.D., CSCS

Dr. Todd Greenberg is a practicing physician with a broad range of expertise, including wellness, exercise, sports injuries, and MRI of sports injuries. He is a Radiology Clinical Associate Professor at the University of Washington.

Additional Information on Obstructive Sleep Apnea

Why Can’t I Sleep? – Clinical Explanations

Sleep Stages

What is Age Management Medicine?

Defy Your Age

Watch Now: 3 Tips for Better Sleep

Sources on OSA

[1] Young et al. “The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults.” The New England Journal of Medicine. 1993. Retrieved from URL:

[2] Weaver, T.E., and Grunstein, R.R. “Adherence to continuous positive airway pressure therapy: the challenge to effective treatment.” Proceedings of the American Thoracic Society. 15 Feb. 2008. Retrieved from URL:

Sleep plays an important role in dealing with stress and reducing inflammation, individuals who cannot recall the last night of sleep that lasted seven to nine hours need to consider seeking help in order to prioritize their sleep schedules

Sleep Stages

The human body has been conditioned to recognize patterns of restfulness and sleep times over thousands of years. The circadian rhythm encompasses physical, mental, and behavioral changes taking place over a daily cycle, which is a result of exposure to light and darkness in our environment. This rhythm is responsible for dictating the drive to sleep not only in humans and animals, but it also plays a role in the functionality of plants and microscopic organisms.[1]

Daylight is among the most powerful influencers compelling us to sleep. When our eyes pick up light rays, they are converted into electrical waves that pass to the optic nerve. Thereafter, the optic nerve relays the message to the body’s “Master Clock,” or the Superchiasmatic Nucleus (SCN), which acts as a master circadian pacemaker controlling the timing of sleep-wake cycles.[2] The SCN comprises thousands of neurons which work in tandem with one another to relay messages across the entire body. As the day winds down and the sun begins to set, the optic nerve then relays this new message to the SCN, which then releases serotonin. Our bodies convert serotonin into melatonin, allowing us to relax and ease into the first stage of sleep.

Textbook of Age Management Medicine Volume 1 is available on Amazon, Cenegenics Senior Physician Jeffrey Leake is the co-author of the Textbook of Age Management MedicineIn the Textbook of Age Management Medicine: Volume 1, authors Jeffrey P. Leake, MD and Todd D. Greenberg, MD note that sleep is classified into three separate phases: wakefulness, non-rapid eye movement (REM) sleep, and REM sleep. Joshua D’Alessandro, New York City-based Nutrition and Exercise Counselor, explains that these categories are further classified into the five stages of the sleep timeline:

  • Sleep Stage 1: After the first ten minutes of sleep, we remain aware of the environment around us. This cycle is brief, lasting seven minutes at most.[3] During this phase, we remain relatively alert and can be woken easily. To facilitate a transition into the next stage, it is recommended that individuals aim to minimize disruptive sounds and shut off all lights.
  • Sleep Stage 2: The second stage occurs within 10 to 20 minutes of initiating sleep. At this point, the SCN has released melatonin, which is taking effect throughout the organs and muscles. This is also when the body begins to slip into a deeper state of sleep.
  • Sleep Stages 3 & 4: Usually within the first 30 to 40 minutes of sleep, we slip into progressively deeper levels of sleep. Known as “Slow Wave Sleep,” (SWS) these stages are particularly difficult to awaken from and often lead to grogginess if interrupted.[4] The pituitary gland releases the appropriate hormones during these phases as well, effectively increasing the release of growth hormones and other androgen hormones. Growth hormones are responsible for muscle protein synthesis, the efficient storage of fuel, restoration of metabolism, and overall recovery. It is therefore absolutely essential that we stay asleep during this phase, which comes just before REM sleep. We will examine the relationship between sleep and hormones in greater detail in an upcoming section.
  • Sleep Stage 5: The fifth stage, REM sleep, comprises roughly 25% of the entire sleep cycle and occurs first within 70 to 90 minutes after falling asleep. Because the sleep cycle repeats, REM sleep is experienced multiple times each night. REM cycles can last for up to 90 minutes, and it is recommended that the body achieves around six full REM cycles to maximum recovery. This can add up to seven to nine hours of sleep.
    REM sleep stimulates the areas of the brain used for learning, and lack of REM sleep is linked to health conditions such as migraines. During REM sleep, signals are sent to the spinal cord to halt movement. Dreaming also occurs during REM.[5]

In individuals who cannot recall the last night of sleep lasting seven to nine hours, serious changes need to be made to rearrange schedules for prioritizing slumber.

Key Resources

This guide was produced with contributions from the following key resources:

The Cenegenics Education and Research Foundation

The Textbook of Age Management Medicine Volume 1: Mastering Healthy Aging Nutrition, Exercise and Hormone Replacement Therapy

Available for purchase here

Joshua D’Alessandro

Nutrition and Exercise Counselor | Cenegenics New York City

Textbook Authors:

Jeffrey Park Leake, M.D., CPT

Dr. Jeffrey Park Leake is a Partner and Director of Education at Cenegenics Elite Health specializing in age management and wellness. Having trained hundreds of physicians worldwide, Dr. Leake is also the Director of Education for the Clinical Strategies for Healthy Aging course at AMM Education Foundation.

Todd David Greenberg, M.D., CSCS

Dr. Todd Greenberg is a practicing physician with a broad range of expertise, including wellness, exercise, sports injuries, and MRI of sports injuries. He is a Radiology Clinical Associate Professor at the University of Washington.

Next Steps

Register for your complimentary phone consultation.

We hope the information above assisted you in your research process.

Additional Information

Why Can’t I Sleep? – Clinical Explanations

Sleep Apnea – What is it?

What is Age Management Medicine?

Defy Your Age With Cenegenics

Watch Now: 3 Tips for Better Sleep


[1] “Circadian Rhythms.” National Institute of General Medical Sciences. Aug. 2017. Retrieved from URL:

[2] Moore, R.Y. “Suprachiasmatic nucleus in sleep-wake regulation.” Sleep Med. Dec. 2007. Retrieved from URL:

[3] “Understanding Sleep Cycles: What Happens While You Sleep.” National Sleep Foundation. Retrieved from URL:

[4] “Sleep and Sleep Disorder Statistics.” See above.

[5] “What is REM sleep?” Eunice Kennedy Shriver National Institute of Child Health and Human Development. 01 Dec. 2016. Retrieved from URL:

Patients meet with the Cenegenics physician during the Elite Health Evaluation, Consultations with the physician and clinical staff are including in the Cenegenics Cost, How much does Cenegenics cost is a commonly asked question and is something you can discuss with your physician as it varies by center location

What Does Cenegenics Cost?

Article at a Glance

  • The cost of Cenegenics varies by location, but we encourage you to ask about promotional discounts when you receive your free complimentary phone consultation.
  • The Cenegenics cost includes your initial Elite Health Evaluation which starts with a comprehensive lab panel, and the Gold Standard of diagnostic testing including: DEXA & body composition scan, VO2 Max testing, CIMT test, neuro-cognitive assessment, exercise and nutrition assessment, and your physician consultation.
  • Specialized testing such as telomere, food allergy, and genomic testing is also available at Cenegenics.

While executive health exams at high quality medical institutions are around $5,000 or more, the initial Cenegenics Elite Health Evaluation is less than that despite being the Gold Standard in extensive diagnostic testing and more focused on true preventive and not only disease testing. Cenegenics offers the Elite Health Evaluation starting at $4,495, although costs can vary by location. We do encourage you to ask about any promotional discounts, which may be available.

These costs are all-inclusive. The Elite Health Evaluation includes a comprehensive lab panel taken at your home or office with a phlebotomist, DXA scan to determine your body composition and bone density, VO2 Max testing to measure cardiopulmonary efficiency, CIMT scan to measure the health of your arteries, and other state-of-the-art testing. Cenegenics offers both Elite Health Evaluations for Men and Elite Health Evaluations for Women.

Elite Health Evaluation – Gold Standard Diagnostics

Cenegenics strives to provide superior healthcare by incorporating hormone optimization (when clinically indicated) harmoniously with appropriate exercise, nutrition, and supplementation in customized programs. Cenegenics relies on the science of age management medicine to help identify and meet criteria, which places you in the lowest possible risk category for disease — particularly heart disease, cancer, stroke, diabetes, metabolic syndrome and Alzheimer’s disease — and thereby extending your health span. In order to build your customized program, we start with your initial evaluation.

Comprehensive Lab Panel

The comprehensive lab panel is a state of the art chemistry panel and complete blood count that is the most extensive in the industry. Includes readings on 88 markers, many of which are not included in standard annual physicals. Our comprehensive lab panel is taken at your home or office, at your convenience. Comprehensive labs, such as this, are necessary for the detecting critical changes in your body before they manifest into chronic diseases such as heart disease, cancer, diabetes or worse. By monitoring markers within hormones, decisive steps to enhance your quality of life to decrease body fat, increase muscle tone, increase physical & sexual vitality, improve mental sharpness, improve sleep quality and decrease the risk of age-related diseases.

DEXA & Body Composition Scan

DEXA scan measuring body fat and bone density included in cost of Cenegenics, DEXA giving accurate scan of body composition included in Cenegenics cost

The DEXA Scan is a test that measures total body fat and includes the exact breakdown of bone density, fat tissue, and muscle mass in the body. DEXA is significant more accurate than BMI and hydrostatic weighing. This body composition scan gives you the information necessary to lose stubborn body fat, build more lean muscle, identify health risks, as well as track your physiological response to your nutrition plan and fitness plan.

VO2 Max Cardiovascular Testing

VO2 Max Test measuring cardiovascular endurance and is included in the Cenegenics cost, exercise physiologist testing patients cardio endurance

VO2 Max Testing is a measurement of the maximum amount of oxygen that an individual can utilize during intense exercise to determine aerobic fitness level and heart rate training zones. This measurement is generally considered the best indicator of cardiovascular health and aerobic endurance, and can help shape your exercise plan.

Carotid Intima-Media Scan (CIMT)

Testing patient for risk of heart attack and stroke using CIMT, patient receiving carotid ultrasound during health evaluation is included in Cenegenics cost

Carotid Intima-Media Scan (CIMT) is a specialized ultrasound of the carotid arteries and is used as a preventive measure against heart attack and stroke. The carotid artery transports blood from your heart to your brain. As thickening occurs in the arteries, plaque can silently build up over years, and often the first symptom a person may experience is heart attack. Physicians are able to provide nutrition and lifestyle recommendations, or suggestions for further action depending upon the state of your carotid arteries.

Neuro-Cognitive Assessment

The neuro-cognitive assessment is a comprehensive evaluation of a patient’s cognitive status by specific neurologic domains, i.e. memory, attention, problem solving, language, visuospatial, processing speed motor, and emotion.

Nutrition & Exercise

During the initial evaluation, you will spend time discussing your current exercise & dietary habits in order to determine personal goals which can be achieved with the right food choices and exercise programs, allowing for optimum physical health.

Physician Consultation

During your consultation your Age Management Medicine Certified Cenegenics physician will carefully evaluate and discuss the results of your extensive lab analysis, diagnostics, medical history, nutrition and exercise consultation and lifestyle. Various health and lifestyle topics will be discussed to help design the program that is right for you. Your physician will also discuss key fundamentals including: aging facts, the role of hormones in your health, andropause or menopause, nutraceutical supplementation, low glycemic nutrition, resistance training, cardiovascular exercise, and risk factors related to cardiovascular disease, stroke, Alzheimer’s, diabetes, sleep disorders, weight loss, bone density (osteoporosis and osteopenia), depression, libido/sexual drive, certain cancers and cognitive function.

Specialized Testing

Depending upon your specialized interests, the following tests are also available at Cenegenics.

Heart Disease & Stroke Prevention Program

The Heart Disease & Stroke Prevention Program helps you break free of the limitations of conventional testing, and gives you a more significant, specific and accurate assessment of your cardiac health.

This program is critical for your future health if you have a family history of heart disease or stroke. It helps you avoid future events if you have had cardiovascular disease or had bypass surgery, heart attack or stroke. It is an innovative program designed by four experts in the field – a cardiovascular surgeon and three cardiologists.

Telomere Testing

telomere length helps determine cells aging, testing to determine health of cells, telomere testing is not including in your health evaluation and is not included in the Cenegenics cost

Telomere testing helps measure how well your cells are aging and gives you an opportunity to learn more about your age-related risk factors.

Telomeres provide a tip at the end of each chromosome to protect the cell. Each time the cell divides in order to replicate, the telomere of each chromosome shortens. When a cell’s telomere becomes too short – from replicating, telomere length genetics, lifestyle habits, and/or environmental factors, the cell dies. Therefore, determining telomere length is considered an exceptional biomarker to determine one’s biological vs. chronological age.

Why Get Tested?

  • Telomere Length Matters: Telomere length indicates an overall health status.
  • Inspire Change: Receive a better understanding of the lifestyle habits that impact aging.
  • Better Treatment: Allows physicians to offer a more personalized treatment plan.
  • Set a Baseline: Results are used to set a baseline and can track progress through retesting.
  • Know Where You Stand: Receive a comparison of your results to the results of others of the same demographic.

Micronutrient Testing

Micronutrient testing is a groundbreaking, patented technology at Cenegenics that provides information to help optimize your nutrients. This unique blood test proves a powerful tool in controlling your aging process – measuring specific vitamins, minerals, antioxidants and other essential micronutrients in your white blood cells to determine cellular function.

Real fact: 50% of people taking multivitamins are actually nutritionally deficient. Contributing factors include lifestyle habits (prescription drugs, smoking, alcohol consumption, and even intense exercise), age factors (i.e. lack of enzymes in the gastrointestinal tract), inability to absorb nutrients, chronic illness, and metabolic disposition. This can lead to disease over time, from cardiovascular disease, stroke, cancer, and diabetes to osteoporosis, arthritis, immune disorders and more.

Disease Risk Profile

The Disease Risk Profile provides a precise assessment of 30 individual fatty acids and 5 of the important ratios (such as the ones influencing chronic inflammatory states), as well as percent distributions of fat families, including the Omega-3 and Omega-6 fatty acids. The report of your results includes recommendations to assist in rebalancing your fatty acids for optimal health.

Maintaining a proper balance between the various families of dietary fats may be one of the most important preventative measures a person can take to reduce the likelihood of developing one of the chronic diseases of modern civilization.

Fatty acids were once thought to be nothing more than a stored form of caloric energy. Current research indicates that fatty acids are some of the most essential nutrients in the human diet, critical for cell membrane structure and function and for local “hormonal” signaling. The number of diseases whose clinical course can be improved by fatty acid therapy is huge, including inflammatory disorders, cardiovascular disease, hormonal disorders, autoimmune disorders, forms of arthritis, mental and behavioral disorders, and many cases of senile neurological degeneration.

Food Allergy Testing

Cenegenics offers an advanced food allergy test that identifies possible existing allergies from 93 different foods. These results will help you and your nutrition and exercise counselor better customize a nutrition plan, usually minimizing or even eliminating these foods altogether. This can bring about major improvements in many symptoms and disorders triggered by food, which have now been identified through testing.

Even the perfect nutrition plan can do harm if you are not certain of the foods that can make you ill. Food allergies can cause immune system reactions ranging from runny nose to life-threatening anaphylaxis.

Some of the symptoms that may dissipate with a shift in diet, which eliminates foods that may be causing your chief complaints include:

  • acne, eczema, rashes
  • anxiety
  • autism spectrum disorders
  • candidiasis
  • chronic fatigue
  • chronic infections
  • depression
  • fibromyalgia
  • irritable bowel syndrome
  • leaky gut syndrome
  • migraines
  • movement disorders
  • multiple sclerosis
  • OCD
  • rheumatoid arthritis
  • seizures

Genomic Testing

“Genomic Testing available at Cenegenics, genome analysis can reveal risk of disease, genomic testing is not included in the Elite Health Evaluation and is in addition to the Cenegenics Cost of your Elite Health Program

Cenegenics has partnered with New Amsterdam Genomics (NAG), the world leader in DNA analysis, to provide this state-of-the-art DNA analysis using whole exome sequencing that allows us to contextualize the results and determine the next steps to take towards optimal health.

NAG testing analyzes all 22,000 genes to help identify specific medical issues as well as understand any broader implications related to them. NAG differs from similar programs like 23andMe because NAG uses advanced technology including exome sequencing, whereas 23andMe uses genotyping and only looks at common variants and mutations. NAG is more extensive and thus capable of identifying your risk for disease as well as traits that you do not exhibit but may affect your children in the future.

Your Genome Can Reveal:

  • Pharmacogenomics (optimized medication selection and dosing)
  • Risks for thousands of diseases (e.g. cancer, diabetes, heart disease, etc.)
  • Diet, exercise, and lifestyle recommendations
  • Traits in your DNA you don’t exhibit, but may affect your children
  • Unique features you weren’t aware of
  • Your ancestry

Patient Comment on “How Much Does Cenegenics Cost”

“Don’t confuse Cenegenics with the dozens of hormone-alternative clinics springing up in strip malls all over the country. I’m sorry to tell you that those anti-aging clinics are to Cenegenics what McDonald’s is to the Four Seasons. Cenegenics has a rock-solid track record-20 years of experience with over 35,000 patients. Doctors come from all over the country to get certified in age-management medicine by the non-profit Cenegenics Education and Research Foundation. In a very real sense, Cenegenics wrote the proverbial book on how to do this stuff the right and responsible way. As a doctor friend of mine once joked, don’t shop for bargains in parachutes, scuba diving equipment, or hormone replacement programs.”

~Jonny Bowden, PhD, CNS – Cenegenics Las Vegas Patient

Read the full article by Jonny Bowden featured in Jet Set Magazine

Cost of Cenegenics Elite Health Evaluation – In Conclusion

The cost of Cenegenics Elite Health evaluation is significantly less than other executive health exams at high quality medical institutions, which are often priced over $5,000. The cost of the Cenegenics Elite Health Evaluation varies by center but is always less than that despite being cutting edge diagnostic testing focused on true preventive medicine, not only disease testing.

These costs are all inclusive. The Elite initial evaluation includes a comprehensive lab panel, DXA scan, VO2 Max Test, CIMT, and other state-of-the-art testing, as well as a consultation with a nutrition and exercise expert and your age management medicine trained Cenegenics physicians. Invest in your health today!

Please see the links below for more information on our Elite Health Evaluation and Cenegenics.

How to Schedule Your Elite Health Evaluation

Register for your complimentary phone consultation.

We hope the information above assisted you in your research process.

Additional Information about the Cenegenics Elite Health Programs

What is Cenegenics?

What is Age Management Medicine?

Defy Your Age™ With Cenegenics 

What is Testosterone Replacement Therapy (TRT)?

Cenegenics Elite Health Program: Why You Should Consider Age Management Your Next Investment

Cenegenics is the clinical leader in age management medicine and has treated over thirty five thousand patients, the elite health evaluation focuses on establishing your medical baselines which will help determine the foundation of your programming

Key to Health & Wellness: What is Cenegenics?

Founded in 1997, Cenegenics is the clinical leader in age management medicine having treated over 35,000 patients, 25% of which are physicians and their families. Cenegenics takes a comprehensive approach to preventive medicine enabling patients to achieve optimal health instead of the traditional approach of treating diseases as they arise. Based on an internal study, the average Cenegenics patient reduces their body fat index by 30% in the first year on the program.

Take Back Your Vitality with the Cenegenics Program

Each Cenegenics program is tailored to optimize your health & wellness by addressing issues such as weight management and important genetic markers

Cenegenics provides a partnership that supports a life-changing experience. We proudly offer you access to elite medical experts who remain by your side throughout your transformation. Whether you’re already healthy and looking to take yourself to the next level, or ready to make a change that will benefit you for the rest of your life, Cenegenics will tailor a program to ensure your lifelong goals are met and surpassed. Cenegenics cost is all-inclusive.

The Cenegenics Elite Health Evaluation

Man meeting with exercise physiologist during Cenegenics Health Evaluation, physician establishing baseline during Cenegenics evaluation

The foundation of the Cenegenics program is the Elite Health Evaluation. This full day of testing establishes your hormonal, physiologic and fitness baseline, serving as the basis of your Cenegenics program. The components of the evaluation include:

•  Medical history and lifestyle assessment

•  Comprehensive blood tests

•  Physical evaluation

•  DEXA scan - determines bone density

•  Body composition scan - measures total and regional body fat

•  CIMT (a specialized ultrasound of the carotid arteries) for heart attack and stroke risk assessment

•  Core strength and flexibility assessment

•  VO2 testing - determines your aerobic fitness level and heart rate training zones

•  Neurocognitive testing

•  Open-ended physician consultation

•  Presentation of your plan of action

A Lifetime of Ongoing Health & Wellness

People are often curious about What is Cenegenics?, Cenegenics is the clinical leader in age management medicine, Cenegenics helps shift the paradigm from the traditional disease model in medicine to preventive care

As part of our partnership, your progress on the Cenegenics program will be monitored and evaluated on an ongoing basis, consistently measuring your current state versus your goals.

• Easy access to your clinical team including your physician and exercise and nutrition consultant

• Modifications of your Cenegenics program by your Cenegenics physician based on blood work results and clinical progress

• Ongoing modifications of your exercise plan based on your own fitness level, motivation and lifestyle

• Close monitoring and fine-tuning of your nutrition program to ensure you are getting good results

• Medical grade vitamins and supplements

Additional Cutting-Edge Testing

In addition to your customized program, you may consider additional testing based on your current needs, such as: 

  • Heart Disease & Stroke Prevention Program

  • Genomic (DNA) Testing

  • Telomere Measurement

  • Micronutrient Testing

  • Food Allergy Testing

Reaching Your Health Potential with Cenegenics

Couple with increased zest for life because of Cenegenics program, Couple improved well-being after Cenegenics Elite Health Evaluation, Couple prepares healthy meal to support life-changing program

Cenegenics provides you with a complete life changing program—one built on low-glycemic and anti-inflammatory nutrition, exercise, nutraceutical supplementation and hormone optimization. No single element stands alone. Its effect keeps your body in perfect harmony and supports your prime objective—realizing your health goals and enjoying a life filled with vigor and a heightened sense of well-being.

Cenegenics has helped over 35,000 patients dramatically change their vitality and optimize their health. Visit our Cenegenics Reviews Page to hear about Cenegenics Patients' experiences on the Cenegenics Elite Health Programs.

Cenegenics in the Media

Cenegenics continues to capture media attention around the world, recognized as a leading authority on age management medicine.

Cenegenics’ media exposure includes CNBC, Bloomberg, The Wall Street Journal, GQ, Men’s Health, Forbes, NY Times and more.

What is Cenegenics – In Conclusion

Cenegenics is the clinical leader in age management medicine, providing a preventive approach by offering state-of-the-art comprehensive programs that are tailored to each patient’s health goals.

Next Steps to Schedule Your Health Evaluation with Cenegenics


Our world class physicians create a personalized plan to help you feel 10+ years younger. You'll be more energetic, lose weight, sleep better, have more libido, and think more clearly. Click below to schedule a free consultation with one of our physicians. It's quick + easy. 

Key Resources

This guide was produced with contributions from the following key resources: 

The Cenegenics Education and Research Foundation  

The Textbook of Age Management Medicine Volume 1: Mastering Healthy Aging Nutrition, Exercise and Hormone Replacement Therapy

Click to purchase

The Cenegenics Education and Research Foundation  

The Textbook of Age Management Medicine Volume 2: Mastering Healthy Aging Nutrition, Exercise and Hormone Replacement Therapy

Click to purchase

Textbook Authors:

Jeffrey Park Leake, M.D., CPT

Dr. Jeffrey Park Leake is a Partner and Director of Education at Cenegenics Elite Health specializing in age management and wellness. Having trained hundreds of physicians worldwide, Dr. Leake is also the Director of Education for the Clinical Strategies for Healthy Aging course at AMM Educational Foundation.

Todd David Greenberg, M.D., CSCS

Dr. Todd Greenberg is a practicing physician with a broad range of expertise, including wellness, exercise, sports injuries, and MRI of sports injuries. He is a Radiology Clinical Associate Professor at the University of Washington.

Learn more about how to stay active and motivated over the holidays, your body is less forgiving of sedentary life and binge eating holiday cookies as you age

Staying Motivated, Healthy and Active During and After the Holidays

cenegenicsdecemberStaying on track with fitness and nutrition is difficult at any age, and as we get older our bodies are less forgiving of cookie binges and sedentary lifestyles. The journey to renewed health is a life long commitment, but if you keep a few tips in mind, maintaining your goals and motivation will be easier to manage.

Become a Morning Person
The early hours of the morning present an opportunity for excellence. It’s a quiet time that’s free of the buzz of appointments, social gatherings and dinner parties. If you can acclimate to getting up early, a morning workout will get you feeling energized without the aid of coffee. It will wake you up and focus your motivation for the rest of the day.

Since we tend to be surrounded by the most food in the afternoon and evening, getting your workout in early will make it easier to stay on track. Since you worked so hard in the AM, you’ll be more likely to turn down platters of Christmas cookies and indulgent snacks that will diffuse your calorie burn.

Another advantage of working out in the morning is that it will improve your circadian rhythm. Working out late in the day can make your brain too excited to sleep, but a morning routine will ensure that you’re adequately tired in the evening, reinforcing a regular, healthy sleep schedule that you need to make fitness gains.

Fortify Your Meals Before Indulging
The holiday season can be very intimidating. It’s hard to say no to desserts, treats and finely roasted meats, but with a bit of forethought, you can make sure your nutrition goals aren’t totally derailed.

Before you get started on any meal, try drinking a glass of water first. Most of us aren’t getting the recommended amount of water a day, and dehydration can actually make us feel hungry. Padding your tummy with water will keep you hydrated and also make you feel fuller so that you’re less likely to overeat.

At holiday dinner parties and other events where food is abundant, make sure you begin your meal with choices that are high in protein and low in saturated fat. Eating a lot of vegetables with your main course will also net you the fiber and nutrients you need without the caloric fallout. As long as you make the majority of your meals nutritionally dense, indulging in a small treat after won’t be as affecting.

Make Exercise Fun
A lot of people make the mistake of diving head first into a strenuous exercise program they aren’t ready for. They may stick with it for a few days or even a few weeks, but ultimately they quit because the routine wasn’t fulfilling. Your workouts should be challenging but they should never be something you dread. Maintaining your motivation is all about engaging in activities you’ll actually look forward to doing in the morning.

No matter what workout you choose, it’s always better with a musical accompaniment. Music can help you push further and forget the strain of fatigue and resistance. Dance is also an excellent way to get a cardio workout that you’ll be eager to do. If you’re not much of a runner, remember that walking is just as effective at burning calories and building your cardiovascular health without being high impact.

In addition to more traditional exercises, think outside the box by trying activities like fitness hula hooping using a weighted hula-hoop. Try to experiment and find a variety of activities you enjoy so that you know you’ll be able to commit to a lifestyle of fitness.